Kybella is an injectable prescription drug containing a synthetic version of deoxycholic acid. This bile acid occurs naturally in the human body and plays a key role in lipid metabolism (via the U.S. National Library of Medicine). Its synthetic form was approved by the FDA in 2015. The drug is used to reduce the appearance of moderate to severe submental fullness, or excess fat beneath the chin.
The drug delivers 10 milligrams of deoxycholic acid per milliliter, according to the FDA. One vial has 2 milliliters. After administration, it dissolves fat cells permanently (per Kybella). The FDA states that a single treatment may include up to 50 injections and should not be administered more than once a month. Patients can receive up to six individual treatments. West End Plastic Surgery says that most people need to undergo two to four treatments to achieve noticeable improvements. A typical session lasts about 20 minutes.
In clinical trials, patients had at least a 10% reduction in submental fat, reports the FDA. A 2016 review confirms that Kybella is well-tolerated and "extremely effective," according to the journal Plastic and Reconstructive Surgery. Moderate weight gain doesn't affect the results, says Dr. Paul Ruff at West End Plastic Surgery. However, you can expect to get a double chin after several months or years if you gain a lot of weight. Aging can compromise the results, too, but it won't happen overnight.
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